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With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.

Hamilton's Pharmacopeia

Ultra LSD

Succumbing to viewer requests, Hamilton journeys to Argentina to understand the legend of Anadenanthera, the world's oldest psychedelic.

Bufotenine: In Search of Hataj

After revealing a scientific mystery around Tramadol-addicted cows in Central Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.

Synethetic Ibogaine-Natural Tramadol

Hamilton traces the multi-billion year history of nitrous oxide on Earth and follows a strange noble gas to the Czech Republic.

Xenon: the Perfect Anesthetic?

From X-ray crystallography to vesicular dopamine release, Hamilton travels the country visiting meth labs to understand the process behind a great American folk art.

A Positive Methamphetamine Story

Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

Synthetic Toad Venom Machine

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In this docuseries, Hamilton Morris -- son of Oscar-winning documentarian Errol Morris -- explores the history, chemistry and societal impacts of some of the world's most unique drugs. Hamilton's work is driven by research -- his apartment is filled with books on the subject -- but he takes it beyond that by going to where the drugs are used to experience them first-hand and find out what happens to the people who use the substances. On his journey, Hamilton studies quaaludes in South Africa, where they are the nation's most commonly used recreational drugs, and traces the history of PCP while traveling across America to speak with addicts, dealers and chemists about the substance.

S3 E1 | Synthetic Toad Venom Machine